Junctophilin-4/JPH4抗体

产品货号：

Z19034

中文名称：

Junctophilin-4/JPH4抗体

英文名称：

Anti-Junctophilin-4/JPH4 Antibody

产品规格：

0.1mg

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-Junctophilin-4/JPH4 Antibody
指标别名	JP4;JPHL1;KIAA1831;Junctophilin-4;Junctophilin-like 1 protein;JP-4
克隆性	Polyclonal
检验物种	human,mouse,rat
应用范围	ELISA,WB
基因名称	JPH4
抗体来源	Rabbit
抗体类型	IgG
免疫原	JPH2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human JPH2.The immunogen is located within amino acids 510 - 560 of JPH2.
计算分子量	66kDa
成分	JPH2 Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式	JPH2 Antibody is affinity chromatography purified via peptide column.
浓度	1mg/mL
产品形态	溶液
保存条件	4℃可保存3个月，-20℃可保存1年。
背景资料	Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels.Junctophilins (JPs) are important components of the junctional complexes.JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM.Four JPs have been identified as tissue-specific subtypes derived from different genes:JPH1 is expressed in skeletal muscle,JPH2 is detected throughout all muscle cell types,and JPH3 and JPH4 are predominantly expressed in the brain and contribute to the subsurface cistern formation in neurons.JPH2-null mice died of embryonic cardiac arrest and human patients with mutations in the JPH2 gene showed hypertrophic cardiomyopathy,demonstrating the importance of this protein.Multiple isoforms of JPH2 are known to exist.
Uniprot ID	Q96JJ6
基因名全称	Junctophilin 4
蛋白名全称	Junctophilin 4
推荐稀释比	JPH2 antibody can be used for detection of JPH2 by Western blot at 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested.

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